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Cell therapy has broad applications that range from treating cancer, diabetes, cardiovascular and neurogenerative conditions to tissue regeneration and replacement. CytoSMART offers an excellent range of live-cell imaging systems that can be used to research and manufacture cell therapies. The applications and examples of these live-cell imaging systems will be discussed below.
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This article highlights considerations for more sustainable live-cell imaging. Live-cell imaging enables researchers to determine not only whether, but also when and how certain cellular events occur in culture. Therefore, this technique is increasingly applied in cell research. The environmental footprint of live-cell imaging can be large, although more sustainable alternatives are also available within this experimental procedure. When looking for a live-cell imaging system, the following 5 factors can already increase sustainability with minimal effort: light source, connected computer, data storage, remote monitoring and analysis, and system complexity.
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Laboratory automation is becoming a new reality in scientific research, due to the rapid technological advancement and the numerous benefits offered by this strategy. Here, we explain relevant commonly used terms in the field of laboratory automation, provide factors to be considered before automating a laboratory, summarize requirements for a successfully automated laboratory, and identify typical laboratories and sectors that fulfil the requirements and, therefore, could be easily and successfully automated.
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A recent study by Drews et al. (2021) focuses on examining broad neuroprotective qualities of losartan. The CytoSMART Lux3 FL fluorescence live-cell imager was used to monitor the motility of Aβ-affected astrocytes. To learn more about the use of the CytoSMART devices in life sciences, we asked Dr. Lusine Danielyan a few questions about her experience with using the Lux3 FL for live-cell imaging.
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Avans University is one of the biggest universities of applied sciences in the Netherlands. One of the programs they offer is Biology and Medical Laboratory Research. Last year, Avans received the CytoSMART Lux2 device to use for education purposes. To get an idea about their experiences with the Lux2 system, we got the opportunity to speak with the program's teachers and students about their use of live-cell imaging in the classroom. We want to give a special thanks to Avans for providing us their insights. Go to the interview here.
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CytoSMART and Qkine have partnered with organoid pioneers from Cold Spring Harbor Laboratory, Stemnovate, and Hubrecht Organoid Technology (HUB) to facilitate an open and collaborative discussion about the key challenges facing pharma and biotech companies as they approach this pivotal stage of their organoid R&D programs. In this article, you will find the Q&A session questions and organoid experts' answers.
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Imaging-based fluorescence cell counting represents the most affordable and flexible automated method of cell quantification. It is gaining its popularity among researchers, who recognize that this approach does not only save them time, but also offers numerous advantages over the manual cell counting.
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The emergence of fluorescence tools has started a new era in biological research and enabled us to see and study cellular processes and dynamics that were not possible before.
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Various applications, such as monitoring cell viability, determining transfection efficiency, investigating co-cultures, and analyzing cellular processes, can benefit from the fluorescent labels and their detailed kinetic visualization.
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With advancements in instrumentation, technologies, and the overcoming of a number of technical challenges, live-cell imaging has enabled researchers to study cellular dynamics with enhanced spatial and temporal resolution.
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