Effect of intrabronchial administration of autologous adipose-derived mesenchymal stem cells on severe equine asthma

Authors: Adamič N, Mihevc SP, Blagus R, Kramarič P, Krapež U, Majdič G, Viel L, Hoffman AM, Bienzle D, Vengust M

Stem Cell Research & Therapy, 2022

 

The authors of this study aimed to assess the effect of intrabronchial administration of adipose-derived mesenchymal stem cells (AD-MSC) on the progression of severe equine asthma (SEA) in horses. The Exact (Corning Cell Counter) was used to assess the concentration of AD-MSCs in a sample. Altogether, it was shown that intrabronchial administration of AD-MSC had limited anti-inflammatory effects but improved the clinical signs of SEA at one year.